Waterproofing is the process of making an object or structure waterproof or water-resistant so that it remains relatively unaffected by water or resisting the ingress of water under specified conditions. Such items may be used in wet environments or underwater to specified depths.

Water-resistant and waterproof often refer to resistance to penetration of water in its liquid state and possibly under pressure, whereas damp proof refers to resistance to humidity or dampness. Permeation of water vapour through a material or structure is reported as a moisture vapor transmission rate (MVTR).

The hulls of boats and ships were once waterproofed by applying tar or pitch. Modern items may be waterproofed by applying water-repellent coatings or by sealing seams with gaskets or o-rings.

Waterproofing is used in reference to building structures (such as basements, decks, or wet areas), watercraft, canvas, clothing (raincoats or waders), electronic devices and paper packaging (such as cartons for liquids).